Removal of Cefixime from Water Using Rice Starch by Response Surface Methodology

en 33014314 Removal of Cefixime from Water Using Rice Starch by Response Surface Methodology Background: Remaining pharmaceutical compounds cause environmental pollution. Therefore, refining these compounds has become a major challenge. In this study, the function of eliminating Cefixime (CFX) using rice starch was evaluated under controlled conditions. Methods: Response Surface Methodology (RSM) was used to design, analyze, and optimize experiments, and the interaction between four variables including pH (3-9), rice starch dose (0–300 mg/L), CFX initial concentration (0–16 mg/L) and time (20–120 min) was investigated on CFX removal. Results: The optimum pH, starch dose, initial concentration and time were 4.5, 225 mg/L, 7.9 mg/L and 95 min, respectively. The maximum efficiency of CFX removal was 70.22%. According to RSM, this study follows a quadratic model (R2=0.954). Conclusion: Rice starch has been successful in removing CFX from the aqueous solution. Therefore, it is recommended to utilize this process to remove CFX from aqueous solutions. Cefixime, Response surface methodology (RSM), Rice starch 230 235 https://www.ajmb.org/En/Article.aspx?id=30434 https://www.ajmb.org/PDF/En/FullText/30434.pdf Fatemeh SadatTabatabaeiDepartment of Environmental Health Engineering, Faculty of Health, Qom University of Medical Sciences, Qom, Iran51637MahdiAsadi-Ghalhari 51638RahimAaliDepartment of Environmental Health Engineering, Faculty of Health, Qom University of Medical Sciences, Qom, Iran51639FatemehMohammadiDepartment of Environmental Health Engineering, Faculty of Health, Qom University of Medical Sciences, Qom, Iran51640RoqiyehMostafalooDepartment of Environmental Health Engineering, Faculty of Health, Qom University of Medical Sciences, Qom, Iran51641RezvanehEsmaeiliDepartment of Environmental Health Engineering, Faculty of Health, Qom University of Medical Sciences, Qom, Iran51642ZohrehDavarparastDepartment of Environmental Health Engineering, Faculty of Health, Qom University of Medical Sciences, Qom, Iran51643ZahraSafariDepartment of Environmental Health Engineering, Faculty of Health, Qom University of Medical Sciences, Qom, Iran51644