en 23408482 Methanolic extract of whole plant of Amaranthus viridis L (MEAV), was screened for antinociceptive activity using acetic acid induced writhing test, hot plate test and tail immersion test in mice. In a similar way a screening exercise was carried out to determine the antipyretic potential of the extract using yeast induced pyrexia method in rats. Administration of the extracts was applied to both laboratory animals at the doses of 200 and 400 mg/kg body weight, respectively. The results of the statistical analysis showed that MEAV had significant (p<0.01) dose dependent antinociceptive and antipyretic properties at 200 and 400 mg/kg. Hence present investigation reveals the antinociceptive and antipyretic activities of methanolic extract of Amaranthus viridis. Analgesics, Animals, Dose response relationship, Methanol, Plant extracts 167 171 https://www.ajmb.org/En/Article.aspx?id=22 https://www.ajmb.org/PDF/En/FullText/22.pdf BagepalliSrinivas Ashok KumarDepartment of Pharmacognosy, Sri K.V.College of Pharmacy, Chickballapur , Karnataka, India71KurubaLakshmanDepartment of Pharmacognosy, PES College of Pharmacy, Bangalore , Karnataka, India72KoralaKonta Narsimha JayaveeraDepartment of Chemistry, Jawaharlal Nehru Technological University of College of Engineering, Anantapur , Andhra Pradesh, India73DevangamSheshadri ShekarDepartment of Pharmacology, Sri K.V.College of Pharmacy, Chickballapur , Karnataka, India74ChinnaSwamyVel MuraganDepartment of Pharmacology, Sri K.V.College of Pharmacy, Chickballapur , Karnataka, India75BachappaManojDepartment of Pharmacognosy, Sri K.V.College of Pharmacy, Chickballapur , Karnataka, India76